Silk Fibroin-Platelet Rich Plasma Injectable Hydrogel with Controlled-Release of Growth Factors for Knee Osteoarthritis
Osteoarthritis (OA) is one of the most common articular diseases globally [1]. Its symptoms include pain and stiffness of the joint, resulting in significant disability and morbidity of the affected population [2]. OA can be classified into primary and secondary according to its aetiology, with the former comprise the majority of the cases. Primary OA is multifactorial in nature and is caused by mechanical stress, inflammation, immunity, genetics and metabolism.
Source: ScienceDirect
